Dr. Bruce R. Hamaker
General Research Areas
- Carbohydrates and health
- Cereal chemistry
Specific Research Areas
- Manipulation of starch digestion rate for low glycemic response/slow digestion
- Dietary fiber, modifications in functionality and fermentability, microbiota changes
- Cereal starch and protein functionality
- Textural properties influenced by starch fine structure
- Interactions between starch and other food components
- Appropriate methods of improving cereal utilization in developing countries
- Cereal endosperm texture
- Electron and confocal microscopy of cereal components
- Rumpagaporn, P., Reuh, B.L., Kaur, A., Patterson, J.A., Keshavarzian, A., Hamaker, B.R. 2015. Structural features of soluble cereal arabinoxylan fibers associated with a slow rate of in vitro fermentation by human fecal microbiota. Carbohydrate Polymers 130:191-197.
- Zhang, G., Hasek, L.Y., Lee, B-H., Hamaker, B.R. 2015. Gut feedback mechanisms and food intake: a physiological approach to slow carbohydrate bioavailability. Food & Function, 6:1072-1089.
- Hamaker, B.R., Tuncil, Y.E. 2014. A perspective on the complexity of dietary fiber structures and their potential effect on the gut microbiota. Journal of Molecular Biology 426:3838-3850.
- Lee, B.H., Lin, A.H.M., Nichols, B.L., Jones, K., Rose, D.R., Quezada-Calvillo, R., Hamaker, B.R. 2014. The mucosal C-terminal maltase-glucoamylase quickly digests large maltooligosaccharides that may contribute to rapid postprandial glucose generation and the high glycemic spike. Molecular Nutrition and Food Research, 58:1111-1121.
- Lin, A. H-M., Nichols, B.L., Quezada-Calvillo, R., Rose, D.R., Hamaker, B.R. 2012. Starch source influences dietary glucose generation at the mucosal ?-glucosidase level. Journal of Biological Chemistry 287:36917-36921.
- Lee, B.H., Eskandari, R., Jones, K., Reddy, R.K., Nichols, B.L., Rose, D.R., Hamaker, B.R.*, Pinto, B.M.* 2012. Modulation of starch digestion for slow glucose release through "toggling" of activities of mucosal a-glucosidases. Journal of Biological Chemistry 287:36917-36921. (* indicates co-corresponding authors)
- Lin, A.H.M., Nichols, B.L., Ao, Z., Quezada-Calvillo, R., Avery, S.E., Sim, L., Rose, D.R., Naim, H.Y., and Hamaker, B.R. 2012. Unexpected high digestion rate of cooked starch by the ct-maltase-glucoamylase small intestinal mucosal a-glucosidase subunit. PLoS ONE 7(5): e35473. doi:10.1371/journal.pone.0035473.
- Fevzioglu, M., Campanella, O.H., and Hamaker, B.R. 2010. Studies on the improvement of the elastic component of corn zein doughs. American Association of Cereal Chemists International annual meeting, Savannah, GA, October.
- Lin, A.H.M., Nichols, B.L., Quezada-Calvillo, R., Rose, D.R., Sim, L., and Hamaker, B.R. 2010. Starches with different fine structures are digested differently at the human brush border level. Institute of Food Technologists annual meeting, Chicago, IL, July.
- Rumpagaporn, P., Campanella, O.H., and Hamaker, B.R. 2010. Heat and pH stability of corn alkali-extractable arabinoxylan and its xylanase-hydrolyzate and their viscosity behavior. Institute of Food Technologists annual meeting, Chicago, IL, July.
- Rose, D.J., Patterson, J.A., and Hamaker, B.R. 2010. Structural differences among alkali-soluble arabinoxylans from maize (Zea mays), rice (Oryza sativa), and wheat (Triticum aestivum) brans influence human fecal fermentation profiles. Journal of Agricultural and Food Chemistry 58:493-499.
- Rose, D.J., Venema, K., Keshavarzian, A., and Hamaker, B.R. 2010. Starch-entrapped microspheres show a beneficial fermentation profile and decrease in potentially harmful bacteria during in vitro fermentation in fecal microbiota obtained from patients with inflammatory bowel disease. British Journal of Nutrition 103:1514-1524.
- Zhang, G. and Hamaker, B.R. 2009. Slowly digestible starch: concept, mechanism a proposed extended glycemic index. Critical Reviews in Food Science and Nutrition 49:852-867.